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As director of the Washington Centre for Weight Management and Research, Domenica Rubino has become frustrated with growing perceptions over the last three years that weight loss drugs such as Novo Nordisk's Ozempic and Wegovy, and Eli Lilly's Mounjaro, are permanent cures for obesity

While natural presence in the body is reassuring, supplementation introduces higher concentrations than the body typically manages, which can occasionally lead to side effects, particularly in vulnerable populations or when combined with certain medications

GLP-1 receptors in the hypothalamus and brainstem reduce hunger signals

10.1016/S0074-7696(07)57004-X 20 DavilaH

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