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Oral BPC-157 is ideal for individuals with digestive disorders including gastric ulcers, leaky gut syndrome, inflammatory bowel conditions, chronic GI inflammation, NSAID-induced gastric damage, food sensitivities related to intestinal permeability, or those seeking systemic healing support through gut health optimization

Kent SBH (2009) Total chemical synthesis of proteins

"Stable gastric pentadecapeptide BPC 157 in trials for inflammatory bowel disease (PL-10, PLD-116, PL 14736, Pliva, Croatia)

It helps to promote anti-inflammatory cytokine activity and reduce pro-inflammatory cytokine activity

However they also show differences in the overall fold with the presence of a DsbA-like domain inserted within the N-terminal thioredoxin-like domain 6