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GLP-1Ra GLP-1Ra were first marketed for the treatment of T2D (at a lower dose and as daily SC injections), then as weekly injections and finally, at larger doses for the treatment of obesity

Treat patients with noncirrhotic metabolic dysfunction-associated steatohepatitis (MASH), previously called nonalcoholic steatohepatitis (NASH), with moderate to advanced liver fibrosis (stages F2 to F3)

When injected into the fat beneath the chin, Kybella destroys these fat cells, resulting in reduced fullness under the chin

Some patients report more or less injection site discomfort with compounded versions compared to brand-name, though this is highly individual

Once et al