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Morphological parameters, blood pressure, electrocardiogram, inflammatory cytokine level, antioxidant levels, brain and heart biomarkers, and histology were evaluated to investigate the protective effects

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4.It was placed on the FDA Category 2 compounding ban list in late 2023

The SURMOUNT-1 study was a placebo-controlled 72-week trial in obese subjects that randomized 2,539 participants without diabetes into four equally large study arms with placebo or one of the three tirzepatide doses (5, 10, or 15 mg once weekly)

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