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The mechanism doesnt eliminate pleasure entirely patients still enjoy meals and social situations but it quiets the compulsive more, more, more signal that characterizes both binge eating and heavy drinking

J Immunol 143:197481, PMID: 2789253 Markovic J, Borrs C, Ortega A, Sastre J, Via J, Pallard FV (2007) Glutathione is recruited into the nucleus in early phases of cell proliferation

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