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Mol Neurobiol 61(10):83448360 Gross EC, Lisicki M, Fischer D, Sndor PS, Schoenen J (2019) The metabolic face of migraine - from pathophysiology to treatment

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Figure 10 In addition to the sulfonamides, e.g., 40 and 41 , the spiro-oxindole dihydroquinazolinone derivative 42 was identified in the screening campaign and subsequently a large series of related analogues were made, e.g., by applying rapid MW-assisted reactions and thereafter examined as IRAP inhibitors in bioassays (Engen et al., 2020) (Figure 10)

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