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If you start at a very high BMI, do not panic if the first 12 weeks produce modest results

De Araujo is finding that adverse reactions might be caused by how the drug differs from the naturally occurring peptide hormone: The hormone acts mostly locally and degrades quickly, while the medicine works mainly on the brain and is designed to stick around in the body

The targets reflect where the underlying peptides have been studied: tendons and ligaments, muscle strains, slow-healing wounds, and the gut lining

These therapies are increasingly recognized for their benefits in managing cardiovascular, renal, and metabolic conditions, which are common comorbidities among patients with T2D