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152 Proteomic profiling further identifies MDR1 upregulation as a critical driver of both intrinsic and acquired resistance to proteolysis-targeting chimeras (PROTACs), extending its relevance to emerging targeted protein degradation strategies
Dihexa functions by increasing the levels of brain-derived neurotrophic factor (BDNF), a key protein involved in the growth, maintenance, and survival of neurons
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It has been widely investigated in experimental research settings for its potential biological activity