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10.1210/jc.2005-2220 77 LiuJ.ZhuD
Targeting IL-17 and TH17 cells in chronic inflammation
Caroline Apovian, former co-director of the Center for Weight Management and Wellness at Brigham and Women's Hospital, has noted: "GLP-1 agonists slow gastric motility, which can paradoxically worsen reflux symptoms in some patients during the titration period, even though the ultimate weight loss tends to improve GERD long-term." A practical monitoring framework for patients on both medications: Weeks 1 to 4 (semaglutide 0.25 mg): Baseline GI symptom assessment
When taken once weekly for 68 weeks alongside a reduced-calorie diet and increased exercise, this dose led to a 9.64% reduction in body weight
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