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You should not take Contrave if you: have uncontrolled high blood pressure have or have had seizures or an eating disorder like anorexia or bulimia are currently using opioid pain medications or are in opioid withdrawal take other medicines containing bupropion drink a lot of alcohol and suddenly stop have taken a monoamine oxidase inhibitor (MAOI) in the last 14 days You should use caution with Wegovy if you: have had problems with your pancreas or kidneys have type 2 diabetes and a history of diabetic retinopathy are taking insulin or other diabetes medications, as Wegovy can increase the risk of low blood sugar (hypoglycemia) Pregnancy and breastfeeding Neither drug is recommended during pregnancy, as weight loss offers no benefit to the fetus and may cause harm

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You should not change your dosing regimen or stop taking Ozempic (semaglutide) as prescribed without discussing with your provider first

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CB4211 is an analog, not native MOTS-c