Therefore, disruptions in PLP synthesis in a person with MTHFR variations may lead to issues with amino acid metabolism, homocysteine levels, and neurotransmitter synthesis, as well as glycogenolysis
Sterility is another issue since many take BPC-157 by injection, any contamination in the preparation could cause infections or other reactions
BPC-157 is not a miracle cure, but its one of the most promising anti-aging peptides in modern medicine
Neuroprotection research includes hippocampal ischemia-reperfusion models in rats (PMID 32558293) and investigations into the brain-gut axis as a candidate explanatory framework for the broad effects observed across tissue types (PMID 27138887)
In preclinical models it has been associated with cytoprotection , modulation of nitric-oxide pathways and angiogenesis , with reported activity across gastrointestinal, musculoskeletal and other tissues [1] [2]