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As a result of that, initial recommendations focus on the use of metformin or a thiazolidinedione if metformin is contraindicated, followed by a GLP-1 agonist or a DPP-4 inhibitor
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In November 2024, the FDA updated the warnings for all GLP-1 agonist and GLP-1 / GIP agonist medicines to note that these agents can increase the risk of food or liquid getting into your lungs (called pulmonary aspiration) during procedures or surgery while you are under deep sedation or general anesthesia
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